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For example, most males are taller and stronger than females, The most obvious differences between males and females include all the features related to reproductive role, notably the endocrine (hormonal) systems and their physiological and behavioral effects, including gonadal differentiation, internal and external genital and breast differentiation, and differentiation of muscle mass, height, and hair distribution.There are also differences in the structure of specific areas of the brain.Through the process of meiosis and fertilization (with rare exceptions), each individual is created with zero or one Y-chromosome.

Gender-based medicine, also called "gender medicine", is the field of medicine that studies the biological and physiological differences between the human sexes and how that affects differences in disease.Chromosomal make up is important in human psychology.Women have two X chromosomes while males have an X and Y chromosomal structure.Therefore, direct sex differences are usually binary in expression (although the deviations in complex biological processes produce a menagerie of exceptions).These include, most conspicuously, male (vs female) gonads.

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